Desvendando o potencial do biossurfactante produzido por Pseudomonas aeruginosa a partir de resíduos agroindustriais da Amazônia como agente estabilizador e formador de nanoemulsões antibacterianas
DOI:
https://doi.org/10.17921/1415-6938.2025v29n2p376-396Resumo
Copaíba (Copaifera L.) e andiroba (Carapa guianensis Aubl.) são árvores tropicais nativas da região amazônica, comumente processadas para extrair óleos com diversas aplicações nutricionais, econômicas e farmacológicas. Esses óleos exibem propriedades antimicrobianas contra uma ampla gama de bactérias, incluindo aquelas responsáveis pela mastite bovina, uma condição inflamatória prevalente que afeta as glândulas mamárias das vacas. No entanto, devido à sua natureza hidrofóbica, a formulação de terapias eficazes usando esses óleos apresenta desafios. Além disso, o descarte inadequado de subprodutos do processamento dessas árvores, particularmente a andiroba, resulta em repercussões econômicas, sociais e ambientais significativas. Este estudo investigou o uso potencial da biomassa residual do processamento do fruto da andiroba para a produção de um biossurfactante ramnolipídico pela bactéria Pseudomonas aeruginosa, designada como BSAW. O BSAW serve como um agente estabilizador e formador para uma nanoemulsão óleo-água contendo óleo de copaíba (NEBSAW) por meio de métodos de alta energia, com propriedades antibacterianas contra bactérias causadoras de mastite bovina. Demonstrando índices favoráveis de rendimento e atividade emulsificante, o BSAW auxiliou no encapsulamento do óleo de copaíba, garantindo a estabilidade física do NEBSAW e aumentando seu efeito antimicrobiano, particularmente contra Streptococcus agalactiae, Klebsiella spp. e Corynebacterium bovis. Este estudo destacou o potencial de aproveitar a biomassa residual do processamento de frutas amazônicas para desenvolver bioprodutos ecologicamente corretos e comercialmente competitivos. Esta abordagem fortalece o valor dos biossurfactantes ramnolipídicos como alternativas ambientalmente viáveis para o desenvolvimento de nanoemulsões, acentuando a importância da biodiversidade regional no fomento de soluções inovadoras e ecologicamente conscientes.
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Copyright (c) 2025 Yara Gomes Da Conceição, Giulian César Da Silva Sá, Alan Moura Feio, Lucas Mariano De Siqueira Pimentel, Joane De Almeida Alves, Glenda Soares Gomes, Evelly Oliveira Ramos, Viviane De Oliveira Freitas Lione , Kattya Gyselle De Holanda e Silva , Ulisses De Pádua Pereira, Pamela Dias Rodrigues, Cristina Maria Quintella , Emilly Cruz Da Silva, Pedro De Sousa Quevedo, Sidnei Cerqueira Dos Santos
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